A one-shot germinal center model under protein structural stability constraints
نویسندگان
چکیده
منابع مشابه
Dynamics of One-pass Germinal Center Models
During an immune response, the affinity of antibodies that react with the antigen that triggered the response increases with time, a phenomenon known as affinity maturation. The molecular basis of affinity maturation has been partially elucidated. It involves the somatic mutation of immunoglobulin V-region genes within antigen-stimulated germinal center B cells and the subsequent selection of h...
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ژورنال
عنوان ژورنال: Physical Biology
سال: 2013
ISSN: 1478-3967,1478-3975
DOI: 10.1088/1478-3975/10/2/025001